Rao, who holds the Guinness Book of Records for directing 125 films in Telugu, Tamil and Hindi, died at a private hospital due to health complications. The National Award-winning director had produced 50 other films.
He had been in and out of hospital for quite some time and had undergone surgery for infection in the lungs and kidneys earlier this year.
Rao, who was a Minister in the Council of Ministers headed by Manmohan Singh, was also chargesheeted in the coal scam.
Some of his famous films include “Premabhishekam”, “Megha Sandesham”, “Osey Ramulamma” and “Tata Manavadu”.
Rao had planned to make a biopic on late Tamil Nadu Chief Minister J. Jayalalithaa.