In the special episode, he will be mocking Republican presidential nominee Donald Trump, reports ew.com.
Alexander will voice the character Bourbon Verlander, a graduate from Yale University who started a scheme of for-profit colleges.
“He has a very evil scheme that is a little reminiscent of the film ‘Ex Machina’, where he has an army of androids built to capture all the student loans that the government is giving out,” executive producer Al Jean said.
“The Simpsons” currently airs in India on Star World and Star World HD. The episode will air in early 2017.