An entirely new approach has been identified by Indian-American researchers in treating high blood sugar which can lead to a great relief to patients suffering with type 2 diabetes. The study, published in the Journal Of Biological Chemistry was a result of collaboration between an Indian female research scholar – Shireesha Sankella and a Professor of Medicine Anil Agarwal, working at University of Texas’ Southwestern Medical Center.
The method is based on the identification of lipid molecules called phosphatidic acids which aid in enhanced production of glucose in the liver. Inhibiting or removing these acids should reduce glucose production, the study assumes.
“We expected the levels of phosphatidic acids to go down. However, in examining the livers of these lipodystrophic mice, we unexpectedly found high levels of this lipid class,” added lead author Shireesha Sankella. This led to the identification of new targets involved in the production of phosphatidic acids. “Besides revealing a new potential therapy to test for treatment of diabetes, the findings may have implications in understanding how cancer develops,” the other researcher Agarwal noted.